48 Hour Fast Benefits

Written by Andrew Brewer. ⚕️Reviewed and fact checked by our medical team.

48 Hour Fast BenefitsPartaking in a 48-hour fast can be challenging, but it’s worth it. You’ll notice a lot of benefits following your fast. Whether you’re looking to add this fast consistently to your routine or simply to kickstart your weight loss journey, let’s discuss some of the most important benefits of a 48-hour fast.

Key Takeaways

  • Weight Loss: Fasting for 48 hours can help with weight loss by creating a calorie deficit, prompting the body to burn fat stores. However, it’s important to maintain healthy eating habits after the fast to prevent weight regain.
  • Autophagy: Intermittent fasting triggers autophagy, a cellular process where nonfunctional components are eliminated, promoting cellular health and potentially destroying harmful viruses and bacteria. Breaking the fast ends the autophagy state.
  • Inflammation Reduction: Fasting for more than 24 hours may help reduce inflammation in the body, providing temporary relief from inflammation-related issues and potentially preventing chronic health problems.
  • Disease Risk Reduction: Fasting for 48 hours can be powerful in reducing the risk of serious diseases like cancer, stroke, heart disease, and Type 2 diabetes. It can improve blood sugar levels, insulin sensitivity, and overall health. However, medical consultation is essential, especially if using fasting as a treatment for existing diseases.
  • Balanced Approach: Intermittent fasting should be accompanied by mindful eating during the non-fasting periods. Gorging on food after fasting can cause discomfort, bloating, and hinder the body’s ability to burn excess calories, potentially leading to weight gain. Maintaining a balanced approach to fasting and eating is crucial for optimal results.

Benefits of 48-hour Fasting

People have been fasting for centuries, and there’s a reason this practice continues to grow in popularity – it simply works. You will see health benefits when you fast for 48 hours, and here are some of the most notable.

Weight Loss

The secret to weight loss is that you need to burn more calories than you’re taking in, and when you fast for 48 hours, that certainly will be the case. When you have no more calories, your body still needs to power its important processes. That’s when it starts to burn fat stores.

The longer you fast, the more time you give your body to burn through those reserves. You will notice weight loss, just don’t gorge yourself once you break your fast. Otherwise, you’ll put it back on – and then some.

Promotes Autophagy

Autophagy is when your cells get rid of the parts that are no longer working, recycling itself to only use the viable parts. This means if a part is nonfunctional, it is purged from your body so it doesn’t take up space or slow down your body’s performance. Additionally, it can help destroy viruses and bacteria that can harm cells, so ultimately, it promotes your body’s cellular health.

This important process is triggered by intermittent fasting because your body is being deprived of nutrients, so the body needs to turn to its cells. Anytime you break your fast, your body is kicked out of autophagy.

Reduces Inflammation

Studies suggest that fasting for more than 24 hours can help reduce inflammation in your body. This is for both temporary issues and chronic pain, which can lead to more serious health issues.

Fasting reduces inflammation by reducing your body’s stress, giving it time to heal as it rests during the fasting state.

Reduces Risk of Diseases

Another reason that fasting for 48 hours is very powerful is because it can help reduce the risk of serious diseases, including cancer, stroke, and heart disease. It can also help improve blood sugar levels and insulin sensitivity, reducing the risk of developing Type 2 diabetes.

Keep in mind that intermittent fasting should never be used in place of medical treatment. You should consult your doctor before embarking on intermittent fasting, especially if you are looking to integrate it to help treat existing diseases.

Why Should I Fast?

Intermittent fasting can improve your overall health and well-being. There are so many benefits to intermittent fasting, so once you get over the hunger, you will start to feel the power of this lifestyle.

Remember, your fasting windows are important, but you also want to pay attention to what you eat during your eating windows. Gorging yourself on food once the fast is up will make you feel uncomfortable and bloated. Too, you binge too many calories, and your body doesn’t have an opportunity to burn through it all before it converts to fat.

At the end of the day, if you are looking to step up your intermittent fasting game, it may be worth it to fast for 48 hours. It will be challenging but worth it. The longer you go without eating, the more benefits your body will have as you continue to heal.

Challenge yourself to fast for 48 hours, and keep a journal of how you’re feeling so you can track the positive results.


  • Is fasting for 48 hours safe?

While fasting for 48 hours can be safe for many individuals, it’s crucial to consult with a healthcare professional, especially if you have underlying health conditions or are taking medications. They can assess your specific situation and provide guidance tailored to your needs.

  • Can I drink water during the 48-hour fast?

Yes, staying hydrated is important during fasting periods. Water is generally allowed and encouraged during the fast to prevent dehydration. However, it’s advisable to avoid other beverages that contain calories or artificial sweeteners, as they may disrupt the fasting process.

  • Can I exercise while fasting for 48 hours?

Moderate exercise during a 48-hour fast is generally safe for most healthy individuals. However, intense or prolonged exercise may be challenging due to reduced energy levels. It’s essential to listen to your body and adjust your activity levels accordingly. If you have concerns or specific medical conditions, consult your healthcare provider before engaging in intense exercise during fasting.

  • What can I eat after breaking the 48-hour fast?

When breaking a 48-hour fast, it’s important to reintroduce food gradually and mindfully. Start with easily digestible, nutrient-dense foods like fruits, vegetables, lean proteins, and whole grains. Avoid consuming excessive amounts of food all at once, as it may lead to discomfort. Listen to your body’s hunger cues and eat until you feel satisfied, rather than overeating.

  • Can I do 48-hour fasts regularly?

Regularly practicing 48-hour fasts should be approached with caution. It’s important to maintain a balanced approach to fasting and consider individual factors such as overall health, lifestyle, and personal goals. Consulting with a healthcare professional or a registered dietitian can help you determine an appropriate fasting schedule that aligns with your specific needs.

  • Can I take medications or supplements during the fast?

Prescription medications should be taken as prescribed, even during fasting periods. If you have concerns about how fasting may interact with your medications or supplements, consult your healthcare provider or pharmacist for guidance. They can provide specific recommendations based on your medications and individual circumstances.

  • Are there any side effects of a 48-hour fast?

While many people can safely undertake a 48-hour fast, it’s important to be aware of potential side effects. Some individuals may experience temporary feelings of fatigue, dizziness, headaches, or changes in mood during the fasting period. These symptoms usually subside as the body adjusts. If you experience severe or prolonged side effects, it’s advisable to discontinue the fast and seek medical attention.

Andrew Brewer

Andrew Brewer

Andrew Brewer started Fastingapps.com to give people the guidance that he never received when he was first starting. His goal is to make your goals achievable and to offer you only the best fasting apps that the internet has to offer. You're not on your own - Andrew and the entire family of reviewers at Fastingapps.com are here with you every step of the way!